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insu ciently e ective for the majority of patients
2020-08-30
insufficiently effective for the majority of patients. In recent years sig-nificant research efforts have been made in mouse models to use magnetic nanoparticles for improving loco-regional cancer treatment. Some studies have focused on targeting drug loaded particles to the vicinity of the tumor with t
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STAR METHODS br Detailed methods are
2020-08-30
STAR+METHODS Detailed methods are provided in the online version of this paper and include the following: d KEY RESOURCES TABLE d CONTACT FOR REAGENT AND RESOURCE SHARING d EXPERIMENTAL MODELS B Mice B Bone Marrow Transplantation (G) Representative confocal images of spleen-derived
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br DATA ANALYSIS br All statistical analyses were performed
2020-08-30
DATA ANALYSIS All statistical analyses were performed using SPSS 13.0 for Windows (SPSS, Inc, Chicago, IL). The associ-ation between CCR4 expression and clinicopathologic features was analyzed by the Pearson c2 test. The Kaplan-Meier method was used to draw survival curves that were compared by
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br C G Loiselle L Edgar G Batist
2020-08-28
[19] C.G. Loiselle, L. Edgar, G. Batist, et al., The impact of a multimedia informational intervention on psychosocial adjustment among individuals with newly diagnosed breast or prostate cancer: a feasibility study, Patient Educ. Couns. 80 (2010) 48–55. [29] C. Sedikides, Assessment, enhanceme
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br driver by iMaxDriverW are reported by
2020-08-28
driver by iMaxDriverW are reported by none of the other fifteen computational tools. The iMaxDriverW reported 43, 97 and 43 new driver 1219168-18-9 in BRCA, LUSC and COAD respectively. Additionally, more than 41% of the genes classified as driver by iMaxDriverN are reported as driver by none of t
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br receptor positive MCF breast cancer cells Chen
2020-08-28
receptor-positive MCF-7 breast cancer cells (Chen and Chien, 2014). BBP and DBP were also reported to promote the proliferation and in-vasiveness of estrogen receptor-negative MDA-231 breast cancer cells through AhR/HDAC6/c-Myc signaling pathway (Hsieh et al., 2012). In our study we found that
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br Since some of the interviews took
2020-08-18
Since some of the interviews took place 6 months after diagnosis and we had concerns on reverse causality, we restricted the analysis to individuals who were diagnosed within 1 month, and the results were consistent with our overall results. We observed similar levels of risk, for example, being u
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C after coating st rd and th cycle
2020-08-18
C5: after coating 1st, 3rd, and 5th cycle, respectively). (b) Intensity change of different polarization peaks. (c) Transmission spectra of BP-TFG in different RI medium. (d) Wavelength shift against external RI. 3.4. Label-free detection of NSE biomarkers The anti-NSE bound BP-TFG was employ
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br Introduction br Pancreatic ductal adenocarcinoma PDAC is
2020-08-18
1. Introduction Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer mortality in the United States [1]. In 2017, there were 53,670 new cases and 43,090 deaths resulting from PDAC, which ac-counted for approximately 3% of all new cancer cases and 7% of all cancer deaths
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br A typical dose dependent cytotoxic
2020-08-18
A typical dose dependent cytotoxic effect was apparently noticed in the SRGO treated gastric cancer cell lines (Fig. 5A,B,C). The con-centration required to destruct at least 50% of NPI-0052 is referred as IC50 value. In this study, IC50 values of each formulation were calculated in order to estim
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Phytomedicine br NaCl was purchased from Jos Manuel
2020-08-18
Phytomedicine 63 (2019) 153017 NaCl was purchased from José Manuel Gomes dos Santos, Lda. Lactacystin, 20S proteasome and Suc-Leu-Leu-Val-Tyr-AMC (20S protea-some fluorogenic substrate) were purchased from Enzo Life Sciences, Inc. (Farmingdale, NY, USA). Hydrochloric 771-97-1 was from VWR Int
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br The typical automatic methods applied in image segmentati
2020-08-18
The typical automatic methods applied in image segmentation are specific to different types of microscopy images and stain-ing technologies. The vast majority of these are based on several underlying algorithms: intensity thresholding, multifractal analy-sis, morphology operation, watershed transf
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br Bhattacharyya N Fried MP Benchmarks for mortality morbidi
2020-08-18
[10] Bhattacharyya N, Fried MP. Benchmarks for mortality, morbidity, and length of stay for head and neck surgical procedures. Arch Otolaryngol Head Neck Surg 2001;127(2):127–32. [11] McDevitt J, de Camargo Cancela M, Kelly M, Comber H, Sharp L. Tracheostomy and infection prolong length of stay
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br Association of hCG and
2020-08-14
3.3. Association of hCG and LHCGR L-α-Hydroxyglutaric Acid patterns with patient clinicopathological parameters Statistical analyses revealed that hCG expression was significantly higher in advanced (III/IV) than in early (I/II) stage EOC, and high hCG expression levels were significantly assoc
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br MODEL br Antithrombotics and intraoperative transfusion
2020-08-14
+ MODEL Antithrombotics and intraoperative transfusion 3 Table 1 Preoperative medications reviewed during thecomprehensive geriatric Gly Pro pNA assessment. Therapeutic Category Medications Potentially inappropriate medication Delirium risk Anticholinergics First-generation C