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br Cell cycle analysis br Assessment of
2020-07-26
2.6. Cell cycle analysis Assessment of cell proliferation was evaluated using classic PI staining. Cells were seeded in complete medium in 6-cm culture plates at a density of 1 × 106 cells per well, and controls were incubated in DMSO. Twenty-four hours after plating, the cells were washed thre
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cck8 br Tumor stage no br chosen as the
2020-07-25
Tumor stage, no chosen as the representative sequences of corresponding OTUs. Taxo- nomic assignment of individual datasets were classified against the Greengenes database version 13.8 using both RDP classifier and HP infection, no that were identified as members of Eukarya, Archaea
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br AKT can be activated by upstream kinases In
2020-07-06
AKT can be activated by upstream kinases. In particular, it has been Fig. 4. HK2 activity is required for AKT2-stimulated tumor invasion, tumorigenesis and metastasis. A and B, HCT-116 cell migration assay; C and D, HT-29 cell migration assay; E, HK2 activity is required for AKT2-stimulated
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br Generation of the functional BBB br A previous study
2020-07-06
3.2. Generation of the functional BBB A previous study suggested that an integral BBB can be formed by both human microvascular endothelial cells (hBMVECs) that line cerebral capillaries and the perivascular end-feet of astrocytes under capillary flow (0.1 dyne/cm2)[37]. To establish a fu
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br p paxillin Tyr labeling in the control
2020-03-24
(p) paxillin (Tyr118) labeling in the control and ADD1-overexpressing H1299 cells. Arrows indicate small peripherally located focal adhesions in the control cells. Arrowheads point at enlarged focal adhe-sions in ADD1-overexpressing cells. (E) Immunoblotting analysis of expression and phosphorylat
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br OGDHL as a rate limiting
2020-03-24
OGDHL as a rate-limiting component of a multi-enzyme complex called OGDHC which is associated with neurodegeneration17 has been previously shown to exhibit differentially pro-moter methylation in different tissue types. Epigenetic changes and methylation alterations on the top are now being consid
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br Discussion br PDAC is an aggressive malignancy whose
2020-03-24
4. Discussion PDAC is an aggressive malignancy whose prognosis has not changed in recent decades compared to other cancer types. Late diagnosis of the disease and high chemoresistance of pancreatic tumours greatly restrict available therapeutic options (Adamska et al., 2017), leaving PDAC patie
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br conditions using the designated sensing assay The identic
2020-03-24
conditions using the designated sensing assay. The identical curren-t–concentration calibration plot clearly showed that the [email protected]–C/GCE displayed high sensitivity and linear relationship within 1–2000 μM with a correlation coefficient (R2) of 0.995. The [email protected]–C/GCE ex-hibited high sensitivity (314 μA
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br hybrid peptide Qdot MNP
2020-03-17
hybrid peptide Qdot-MNP is effective for triggering the MNP-mediated hyperthermia for selective treatment of breast cancer cells. 4. Discussion The usefulnees of peptides is manifest by their functionality to endow NPs with the ability of drug delivery. There are four gen-eral methods imp
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Methylpiperidino pyrazole br Armitage JN van der Meulen JH R
2019-11-11
27. Armitage JN, van der Meulen JH; Royal College of Surgeons Co-morbidity Consensus Group. Identifying co-morbidity in surgical patients using administrative data with the Royal College of Surgeons Charlson Score. Br J Surg 2010;97:772-81. 28. Robins JM. A new approach to causal inference in m
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br For testing those hypotheses Kendall
2019-11-06
For testing those hypotheses, Kendall–Theil Sen Siegel nonparametric linear regression [30] was used for simple regressions. Multiple regression was also performed, using a robust linear model [31]. Root mean squared error (RMSE), i.e. residual standard error, has been used as a goodness-of-fit me
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br The most common AEs were nausea diarrhoea and decreased
2019-11-05
The most common AEs were nausea, diarrhoea and decreased appetite (S8). AEs 10% higher with ipata-sertib versus placebo included diarrhoea, vomiting, rash, fatigue, stomatitis, nausea and decreased appetite. Neutropenia was 10% greater in the placebo versus ipatasertib arm. Of note, more patients
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br Funding br Conflict of
2019-10-30
Funding Conflict of interest The authors declare that they have no competing interests. Acknowledgments We acknowledge the contribution of the people who took part in this research, often at a time of great challenge in their lives, thank you. In addition, we thank TCGA and CTD dataset
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br Liu Y Zhao Y
2019-10-22
Liu, Y., Zhao, Y., Wang, Y., & Chang, M. L. (2015). Polyamine-capped gold nanorod as a localized surface Plasmon resonance probe for rapid and sensitive copper(II) CAY10683 detection. Journal of Colloid and Interface Science, 439, 7–11. Zhang, Y., Qian, J., Wang, D., Wang, Y., & He, S. (2013).